In this conversation, Daniel Belkin and Mitch Belkin interview Jean Hébert, PhD about aging, brain plasticity, and progressive neocortical replacement. They discuss one hallmark of aging—extracellular matrix damage—as well as how tissue replacement is a possible solution to aging. In addition, they explore the practicalities of progressive neocortex replacement, dopaminergic neuron transplants in Parkinson's patients, and Professor Hébert's work on stroke.

00:04: Jean Hèbert Introduction
00:52: What is aging?
02:51: Extracellular matrix damage
06:58: Tissue replacement as a possible solution to aging
11:19: Brain plasticity
13:51: Practicalities of progressive neocortex replacement
21:57: Dopaminergic neuron transplants in Parkinson's patients
26:40: Brain tissue replacement in stroke patients
40:37: Rapid fire questions (Cameo by my cat FREEDA KATO!)

Who is Jean Hébert?

Jean Hebert, PhD, is a Professor of Neuroscience and Genetics at the Albert Einstein College of Medicine where he focuses on age-related brain degeneration in the adult neocortex. He is one of the world’s leading researchers on brain cell and tissue replacement. He is the author of the book Replacing Aging.

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