APOE2 is an important protein in the brain. APOE2 has been found to increase longevity in people as well as animals. APOE2 has been found to reduce the risk of Alzheimer's disease. The video is a requested video about doing a deep dive into APOE2. Overall, APOE2 reduces total cholesterol and increases activity which could be why people with APOE2 live longer on average.

Review Paper APOE2:
https://molecularneurodegeneration.bi...
Research Paper APOE2:
https://www.ncbi.nlm.nih.gov/pmc/arti...