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“Fuel the Mind, Heal the Gut, Reclaim Immunity”
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Show Notes:
Most Fatty Lover physicians, specialists, Hepatologists, and gastroenterologists are focused on ordering tests, and prescribing medication. But there are several areas which are commonly overlooked and these mistakes can cause inflammation to increase over time, without resolution

1. Ignoring Bowel Movements- We now know that most fatty liver disease is caused by gut microbiome dysfunction. Mucosa Associated Lymphatic Tissue (MALT), spleen, liver, Aero-Digestive tract- contains 80% of the body's immune system. American Gut Project- Top Tier Research Universities are able to predict liver inflammation, exacerbation, and severity, based on the type of bacteria in the stool. Gut microbiome optimization therefore is very important in the treatment of fatty liver disease. I also have patients with autoimmune hepatitis who get better with this type of intervention. Frequent regular bowel movements are desirable to prevent inflammation. Otherwise you get overgrowth of bacteria, sometimes called SIBO, or IMO if the bacterial produce methane. These bacteria cause the intestinal permeability to increase, result in leaky gut. There are tests you can do for SIBO, IMO, methane production, and Zonulin metabolites for leaky gut. C difficile colitis, also called clostridium bacteria, is another type of opportunistic infection from bacterial overgrowth. You can also get overgrowth of funguses such as Candida, which results in histamine intolerance.

2. Too much sugar, processed foods. There are several concurrent biochemical pathways of inflammation that get activated in fatty liver disease. Reactive oxygen species, oxidative damage. Fatty acid synthase (FAS), hormone-sensitive lipase (HSL), and peroxisome proliferator-activated receptor gamma (PPAR-γ), nuclear factor-kappa B (NF-κB) dysregulation. If you avoid these foods, you can activate protective pathways, that are anti-inflammatory in nature. These protect and heal the liver. These include NADPH oxidase and xanthine oxidase, superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx)

3. Deficiency in Phytonutrients- Long term paleo, carnivore, Atkins, weight watchers diets can be deficient in plant base micronutrients. Many of these nutrients (example: thiocyanates) are capable of fixing fatty liver.

4. Ignoring stress and trauma- Stress can increase inflammation and fatty liver.

5. Poor Sleep- Can cause fatty liver diseae

6. Sedentary Lifestyle- can make metabolism of carbohydrates dysfunctional and cause increased glycogen storage in fatty liver disease.

00:00-01:30: Introduction
01:31-07:33: Bowel Movements Effect Your Fatty Liver
07:34-10:25: Impact of Sugars and Processed Food on Fatty Liver
10:26-13:26: Phytonutrient deficiency in Fatty Liver
13:27-15:46: How Stress and Trauma Impacts Your Fatty Liver
15:47-16:23: Sleep Effects on Fatty Liver
16:24-17:55: Fatty Liver and Exercise
17:56-18:57: Outro

Note:
Although I am a licensed, and practicing surgeon, with over a decade of experience helping people overcome inflammatory diseases such as fatty liver disease, the presented material is intended for educational purposes only and should not be construed as medical advice. Please use your best judgment and consult with a healthcare professional regarding your needs.

If you are looking for personalized medical support, visit MGIclinic.com to work with me.

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"As always: Be TRUE to yourself. Surround yourself with people who affirm your wellbeing. Find a doctor who will slow down to listen. Find one who carefully considers your concerns and most of all--find one who cares."

Dr. Chanu R. Dasari MD