Two bitter enemies end up in each other's bodies, and take the opportunity to ruin each other's lives.
Next door neighbors Nell Bedworth and Woody Deane have opposite behaviors and hate each other: geeky virgin Nell is educated, sensitive and well prepared to go to Yale, while Woody is rude and his highest expectation is to get into a mediocre college because of his soccer playing skills. When Nell and Woody are assigned to visit a museum together, they argue in front of a statue of an Aztec god. During the night, their souls exchange bodies, which leads them into difficult situations. They first try to damage each other's reputation in high school, but soon discover that their dream of going to college can only happen with mutual respect and support.