In this video I'm making the recently discovered broad-spectrum antibiotic Arsinothricin. An arsenic-based non-proteinogenic amino acid analog of glutamic acid. It is an inhibitor of the glutamine synthethase enzyme. Some researchers are working on developing a more convenient synthetic route to Arsinothricin, which would be useful in larger scale production and for tests in trials. It has been decades since a new class of antibiotics has entered the market. In this video, I am following the most recent developed route.

For the first precursor:
https://sci-hub.se/https://doi.org/10...

Rest of synth:
https://pubs.rsc.org/en/content/artic...

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