Scientists have connected two organoids together with an axon bundle, to study how brain areas communicate. They sent signals back and forth and responded to external stimulation.

Learn about: axons, white matter, re-entry, optogenetics, myelination, entrainment, short-term potentiation

CORRECTIONS/CLARIFICATIONS:
As the pinned comment points out, there are many different kinds of neurons, and two pairs of organoids may not have the same cellular makeup. This natural variation between neurons might also account for the different post-stimulation behavior of the organoids from different cell lines.

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Books and audiobooks mentioned (I will get a small commission at no cost to you to support the channel)
- A Universe of Consciousness: How Matter Becomes Imagination (By Gerald Edelman and Giulio Tononi) https://amzn.to/4aLBZED
- Sync: How Order Emerges from Chaos in the Universe, Nature, and Daily Life, (By Steven Strogatz) https://amzn.to/3UyJM3o

The paper (open access) https://www.nature.com/articles/s4146...
Osaki et al., 2024: Complex activity and short-term plasticity of human cerebral organoids reciprocally connected with axons