Avoid 6 Mistakes: Seasonal Allergies, Histamine intolerance (SIBO, IMO, Candida, Leaky Gut, Zonulin)
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 Published On Sep 7, 2023

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Show Notes:
Most Allergy physicians, specialists, allergists, and immunologists are focused on ordering tests, and prescribing medication. But there are several areas which are commonly overlooked and these mistakes can cause inflammation to increase over time, without resolution

1. Ignoring Bowel Movements- Histamine is produced in the gut. Therefore with seasonal allergies, you need to prevent gut level production of histamine. Mucosa Associated Lymphatic Tissue (MALT), spleen, liver, Aero-Digestive tract- contains 80% of the body's immune system. American Gut Project- Top Tier Research Universities are able to predict autoimmune inflammation, exacerbation, and severity, based on the type of bacteria in the stool. Gut microbiome optimization therefore is very important. Frequent regular bowel movements are desirable to prevent inflammation. Otherwise you get overgrowth of bacteria, sometimes called SIBO, or IMO if the bacterial produce methane. These bacteria cause the intestinal permeability to increase, result in leaky gut. There are tests you can do for SIBO, IMO, methane production, and Zonulin metabolites for leaky gut. C difficile colitis, also called clostridium bacteria, is another type of opportunistic infection from bacterial overgrowth. You can also get overgrowth of funguses such as Candida, which results in histamine intolerance and worsening of seasonal allergies.

2. Too much sugar, processed foods. There are several concurrent biochemical pathways of inflammation that get activated and cause allergies. Reactive oxygen species, oxidative damage. Fatty acid synthase (FAS), hormone-sensitive lipase (HSL), and peroxisome proliferator-activated receptor gamma (PPAR-γ), nuclear factor-kappa B (NF-κB) dysregulation. If you avoid these foods, you can activate protective pathways, that are anti-inflammatory in nature. These include NADPH oxidase and xanthine oxidase, superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx)

3. Deficiency in Phytonutrients- Long term paleo, carnivore, Atkins, weight watchers diets can be deficient in plant base micronutrients. These micronutrients can help prevent allergies

4. Ignoring stress and trauma- Stress can lead to histamine release, worsening allergies

5. Poor Sleep- can lead to increased inflammatory markers in seasonal allergies

6. Sedentary Lifestyle- exercise in anti-inflammatory and nature, and counter-acts histamine and allergies in the body. Sometimes you can get exercise related histamine release, so be careful.


00:00-01:30: Introduction
01:31-07:33: Bowel Movements Effect Allergies
07:34-10:24: Impact of Sugars and Processed Food on Allergies
10:25-13:26: Phytonutrient deficiency in Allergies
13:27-15:47: How Stress and Trauma Impact Your Allergies
15:48-16:23: Sleep Effects on Allergies
16:24-17:54: Exercise Importance for Allergies
17:55-18:54: Outro

Note:
Although I am a licensed, and practicing surgeon, with over a decade of experience helping people overcome inflammatory diseases such as allergies, the presented material is intended for educational purposes only and should not be construed as medical advice. Please use your best judgment and consult with a healthcare professional regarding your needs.

If you are looking for personalized medical support, visit MGIclinic.com to work with me.

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"As always: Be TRUE to yourself. Surround yourself with people who affirm your wellbeing. Find a doctor who will slow down to listen. Find one who carefully considers your concerns and most of all--find one who cares."

Dr. Chanu R. Dasari MD

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