Monsters | Awesome Compilation | Learn Math for Kids | Cartoons for Kids
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The city of Monstropolis in the monster world is powered by energy from the screams of human children. At the Monsters, Inc. factory, skilled monsters employed as "scarers" venture into the human world to scare children and harvest their screams, through doors that activate portals to the children's bedroom closets. It is considered dangerous work, as human children are believed to be "toxic". Energy production is falling because children are becoming less easily scared, and company chairman Henry J. Waternoose is determined to find a solution. James P. "Sulley" Sullivan is the organization's top scarer, but his chief rival, chameleon-like monster Randall Boggs, is close behind.

One day, Sulley discovers that Randall has left a door activated on the scare floor, and a small girl has entered the factory. After several desperate failed attempts to put her back, Sulley conceals her and takes her out of the factory. He interrupts his best friend Mike Wazowski's date with his girlfriend Celia, and chaos erupts when the child is discovered. Sulley and Mike manage to escape with the child before the Child Detection Agency (CDA) quarantines the restaurant, and back at their home, discover that she is not actually toxic after all. Sulley grows attached to her and calls her "Boo", while Mike is just anxious to be rid of her.

When they smuggle her back into the factory in an attempt to send her home, Randall discovers her and tries to kidnap her, but mistakenly kidnaps Mike instead. He straps Mike to a large machine called "The Scream Extractor", which he intends to use to revolutionize the scaring industry and solve the monster world's energy problems by forcefully extracting screams from kidnapped human children, though not without harming them in the process. Before Randall can use the machine on Mike, Sulley intervenes and reports Randall to Waternoose. Waternoose, secretly in league with Randall, instead exiles Mike and Sulley to the human world in the Himalayas. The two are taken in by a Yeti, who suggests they travel to a nearby village to return to the monster world. Sulley prepares to leave, but Mike angrily refuses to go with him. Meanwhile, Randall is preparing to use the Scream Extractor on Boo, but Sulley arrives and saves her. Randall and Sulley fight, and after Mike returns and the two reconcile, they overpower Randall, take Boo and flee.

Randall pursues them to the giant door vault, and a wild chase ensues among the millions of doors as they move in and out of the storage vault on rails to the factory floor. Boo's laughter causes all the doors to activate, allowing the chase to pass in and out of the human world. Randall attempts to kill Sulley, but Boo overcomes her fear and attacks him. Sulley and Mike trap Randall in the human world, where two residents at a trailer park beat him with a shovel, mistaking him for an alligator. Sulley and Mike then trick Waternoose into revealing his plot with Randall, while Mike secretly records the entire conversation. The CDA then arrests Waternoose, and Sulley and Mike say goodbye to Boo and return her home before her door is shredded to prevent any more contact with her.

With the factory temporarily shut down, Sulley is named the new CEO of Monsters, Inc. Under his leadership, the energy crisis is solved by harvesting children's laughter instead of screams, as laughter has been found to be much more potent. Mike takes Sulley aside, revealing he has rebuilt Boo's door, and only needs one final piece, which Sulley took as a memento. Sulley enters and joyfully reunites with Boo.