Smelling Isocyanides: The REAL Stinkiest Chemicals On Earth (WAY Worse Than Thioacetone)
LabCoatz LabCoatz
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 Published On Aug 4, 2023

Ever since I made thioacetone for the first time back in 2022, I've been on a quest to find the most offensive smell on Earth...and I think I just might've found a prime candidate: n-butyl isocyanide! This is the only chemical I have ever tested that made me cough and experience discomfort from odor alone. It's not corrosive, irritating, or significantly toxic. It just REALLY reeks.

NOTE: the giveaway has ended, so any money sent for isocyanide will be refunded.

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Be sure to check out @midwestchem368 and his take on the Gabriel synthesis:
Part 1:    • the gabriel synthesis of 1-aminobutan...  
Part 2:    • 100 sub finale. n butylamine / 1 amin...  

A special thanks to @BackYardScience2000 for donating some of his chemicals to my channel! If you ever need specialty reagents, like benzene or phosphorus, be sure to check out his eBay store:
https://www.ebay.com/str/backyardscie...

Need hydrochloric or nitric acid (especially in bulk)? Be sure to check out the excellent selection found at Alchemie Labs:
https://alchemielabs.com/

Want quality glassware at an affordable price? Check out CELL Supplies! If you're into hobby or professional chemistry, I definitely recommend them:
https://www.cell-supplies.com/

WARNING: isocyanides are potentially toxic if inhaled for extended periods of time (some having similar effects to carbon monoxide). Organic amines are also mildly toxic and somewhat corrosive. Do not attempt anything seen in this video unless you understand the risks involved!

0:00 My stinky journey
1:00 The wrong kind of smell
1:29 Isocyanides
2:20 How do you make an isocyanide?
4:09 Aniline synthesis
8:08 Tert-butylamine
8:54 N-butylamine
9:39 Smelling day
11:08 Phenyl isocyanide smell test
12:32 Tert-butyl isocyanide
13:20 N-butyl isocyanide: the VERY worst
14:27 Distilling n-butyl isocyanide
15:02 Stinky problems
16:35 Pure n-butyl isocyanide!
16:55 Oops.
17:25 Distilling the other isocyanides
18:01 What do they smell like?
20:19 Comparing the super-stenches (thioacetone, selenols, and more)
23:36 ISOCYANIDES FOR SALE!
24:03 Sponsor thanks and conclusion

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